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Symptoms

Delirium
Depression
Fatigue
Pain

 
Cancer Fatigue

Fatigue is a highly prevalent and disabling symptom of cancer and side effect of cancer treatment. It affects between 60 and 90% of cancer patients and arises from multiple causes. As prevalent as it is, patients often do not complain about it or view it as a treatable complication of their treatment. Rather they try to grin and bear it. OSCR is presently involved in a study to examine why patients do not report fatigue to try and describe the barriers to better communication. Additionally, we have initiated a screening and algorithm study to treat fatigue and study the impact of this treatment.

Ninety percent of cancer patients suffer from fatigue, and 75% of cancer patients consider fatigue a symptom to live with.  Fatigue is so prevalent because it arises from multiple factors (shown on Table 1).

Table 1:  Factors that Influence Fatigue

Physical Psychological
Pain Depression/Isolation
Sleep/Rest Patterns  Anxiety
Nutrition (cytokines) Stress from Relationship Changes
Medications Stress from Finances
Overall physical condition  
Bone Marrow suppression  
Gastrointestinal problems  

Patients who experience fatigue are not alone.  A reported 60-99% of chemotherapy patients experience fatigue.  Out of the total cancer population 78% experience debilitating fatigue.  Over fifty percent of these patients feel fatigued on most days or everyday.

Factors associated with Chemotherapy Fatigue

  • Pathologic

  • Environmental

  • Psychological

  • Duration of illness

  • Drug interactions

  • Age

Barriers to Fatigue Communication

In a collaborative study with Memorial Sloan-Kettering Cancer Center, we have recently begun to assess the barriers to patient communication of fatigue to their physicians. The study is being administered by Purdue University Ph.D. student, Anne McVey, and will serve a dual purpose as her dissertation thesis. Our goal is to assess 150 cancer patients, 75 each in city and rural settings. This study will evaluate different barriers and any differences that may exist in rural verses a metropolitan environment. Screenings will be  carried out at IOHC-South, IOHC-Main of Indianapolis, Howard Community Hospital in Kokomo, Putnam County Hospital, Wabash County Hospital, Jhtmler County Hospital and Tipton County Hospital.